Benadryl Gluten-Free?

Is Benadryl gluten-free? As a staple in many people’s medicine cabinets, many celiacs wonder if Benadryl is safe for them to take.

I combed through all of the ingredients in Benadryl products and I called Benadryl themselves to get the answer: is Benadryl gluten-free? And more importantly, can you take Benadryl with celiac?

Is Benadryl Glluten-free​ - Tayler Silfverduk, celiac dietitian

Is Benadryl Gluten-free?

I combed through the ingredients of all Benadryl adult formulation to see if they are gluten-free. I could not find gluten anywhere.

But so many people were saying only Benadryl’s Allergy Dye-Free Liquidgels were gluten-free. Why?

I called Benadryl to find out. As of 10/20/2021, here’s what they told me:

  • Benadryls’ Allergy Dye-Free Liquidgels are tested to be gluten-free.
  • Benadryl’s Allergy Plus Congestion Ultratab tablets don’t have gluten containing ingredients but are not tested for gluten content.
  • Benadryl’s Ultratab Tablets also don’t have gluten containing ingredients but aren’t tested for gluten content either.

So Benadryl’s products are gluten-free but only Benadryl’s Allergy Dye-Free Liquidgels have been tested and confirmed gluten-free.

So are Benadryl products safe for celiac disease? Based on this, I’d say it’s up to the individual and their comfort-level.

Some people will want everything they put in their body to have been tested for gluten, and for other people that’s unrealistic. For me, I would take Benadryl products confidently.

If you want to call and speak with a representative for yourself, the number I called was 1-877-717-2824.

What About Risk for Cross-Contact

With celiac disease, you have to worry about cross-contact. However, with medications, the cross-contact risk is generally very low because of the sanitation protocols involve to prevent the mixing of active ingredients that could be harmful.

In this way, as always gluten cross-contact is a risk with Benadryl, but it’s very unlikely with medications due to strict sanitation guidelines to prevent active ingredients from mixing and doing a lot of harm.

If you want to learn more about safety with gluten in medications, I talk about this more in-depth in the Celiac Crash Course.

Can Benadryl Help With Gluten Exposure?

The active ingredient in Benadryl is Diphenhydramine, which according to WebMd, can relieve symptoms related to allergies, hay fever, the common cold, and motion sickness.

There’s not been any research to prove that Benadryl specifically can help with gluten exposure. However in some studies, antihistamines have been shown to help.

Despite lack of research supporting the use of Benadryl, many anecdotal reports from celiacs say that taking it when glutened helps them. And unlike activated charcoal, benadryl is not as dangerous to take. So if it helps you, it may be helpful to keep in you gluten exposure recovery kit.

And if you want more on how to help alleviate gluten exposure symptoms, check out my post “What to do When You’ve Been Glutened“.

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